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Pulmonary embolism (PE) is the main trigger of in-hospital death and the third most frequent trigger of cardiovascular dying. The clinical presentation of PE is variable, and selecting the suitable therapy for individual patients will be difficult. Traditionally, therapy of PE has involved a choice of anticoagulation, thrombolysis or surgical procedure; nonetheless, a variety of percutaneous interventional technologies have been developed which can be under investigation in patients with intermediate-high-danger or excessive-threat PE. These interventional applied sciences embody catheter-directed thrombolysis (with or with out ultrasound help), aspiration thrombectomy and combos of the aforementioned ideas. These interventional therapy choices may lead to a extra rapid improvement in proper ventricular perform and pulmonary and/or systemic haemodynamics in particular patients.